A radiation hybrid transcript map of the mouse genome
Identifieur interne : 00BE12 ( Main/Exploration ); précédent : 00BE11; suivant : 00BE13A radiation hybrid transcript map of the mouse genome
Auteurs : Philip Avner [France] ; Thomas Bruls [France] ; Isabelle Poras [France] ; Lorraine Eley [Royaume-Uni] ; Shahinaz Gas [France] ; Patricia Ruiz [France] ; Michael V. Wiles [Allemagne] ; Rita Sousa-Nunes [Royaume-Uni] ; Ross Kettleborough [Royaume-Uni] ; Amer Rana [Royaume-Uni] ; Jean Morissette [France] ; Liz Bentley [Royaume-Uni] ; Michelle Goldsworthy [Royaume-Uni] ; Alison Haynes [Royaume-Uni] ; Eifion Herbert [Royaume-Uni] ; Lorraine Southam [Royaume-Uni] ; Hans Lehrach [Allemagne] ; Jean Weissenbach [France] ; Giacomo Manenti [Italie] ; Patricia Rodriguez-Tome [Royaume-Uni] ; Rosa Beddington ; Sally Dunwoodie [Australie] ; Roger D. Cox [Royaume-Uni]Source :
- Nature genetics [ 1061-4036 ] ; 2001.
Descripteurs français
- Pascal (Inist)
English descriptors
Abstract
Expressed-sequence tag (EST) maps are an adjunct to sequence-based analytical methods of gene detection and localization for those species for which such data are available, and provide anchors for high-density homology and orthology mapping in species for which large-scale sequencing has yet to be done1. Species for which radiation hybrid-based transcript maps have been established include human2, rat3-5, mouse6, dog7, cat8 and zebrafish9,10. We have established a comprehensive first-generation-placement radiation hybrid map of the mouse consisting of 5,904 mapped markers (3,993 ESTs and 1,911 sequence-tagged sites (STSs)). The mapped ESTs, which often originate from small-EST clusters, are enriched for genes expressed during early mouse embryogenesis and are probably different from those localized in humans. We have confirmed by in situ hybridization that even singleton ESTs, which are usually not retained for mapping studies, may represent bona fide transcribed sequences. Our studies on mouse chromosomes 12 and 14 orthologous to human chromosome 14 show the power of our radiation hybrid map as a predictive tool for orthology mapping in humans.
Affiliations:
- Allemagne, Australie, France, Italie, Royaume-Uni
- Angleterre, Berlin, Grand Londres, Nouvelle-Galles du Sud, Île-de-France
- Berlin, Evry, Londres, Paris, Sydney
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 005756
- to stream PascalFrancis, to step Curation: 000983
- to stream PascalFrancis, to step Checkpoint: 005976
- to stream Main, to step Merge: 00CD21
- to stream Main, to step Curation: 00BE12
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">A radiation hybrid transcript map of the mouse genome</title><author><name sortKey="Avner, Philip" sort="Avner, Philip" uniqKey="Avner P" first="Philip" last="Avner">Philip Avner</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Genoscope, Centre National de Sequençage and CNRS UMR 8030, CP 5706</s1><s2>91057 Evry</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Evry</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Génétique Moléculaire Murine, Institut Pasteur</s1><s2>Paris</s2><s3>FRA</s3><sZ>1 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Bruls, Thomas" sort="Bruls, Thomas" uniqKey="Bruls T" first="Thomas" last="Bruls">Thomas Bruls</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Genoscope, Centre National de Sequençage and CNRS UMR 8030, CP 5706</s1><s2>91057 Evry</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>91057 Evry</wicri:noRegion><wicri:noRegion>CP 5706</wicri:noRegion><wicri:noRegion>91057 Evry</wicri:noRegion></affiliation></author><author><name sortKey="Poras, Isabelle" sort="Poras, Isabelle" uniqKey="Poras I" first="Isabelle" last="Poras">Isabelle Poras</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Genoscope, Centre National de Sequençage and CNRS UMR 8030, CP 5706</s1><s2>91057 Evry</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>91057 Evry</wicri:noRegion><wicri:noRegion>CP 5706</wicri:noRegion><wicri:noRegion>91057 Evry</wicri:noRegion></affiliation></author><author><name sortKey="Eley, Lorraine" sort="Eley, Lorraine" uniqKey="Eley L" first="Lorraine" last="Eley">Lorraine Eley</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Gas, Shahinaz" sort="Gas, Shahinaz" uniqKey="Gas S" first="Shahinaz" last="Gas">Shahinaz Gas</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Genoscope, Centre National de Sequençage and CNRS UMR 8030, CP 5706</s1><s2>91057 Evry</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>91057 Evry</wicri:noRegion><wicri:noRegion>CP 5706</wicri:noRegion><wicri:noRegion>91057 Evry</wicri:noRegion></affiliation></author><author><name sortKey="Ruiz, Patricia" sort="Ruiz, Patricia" uniqKey="Ruiz P" first="Patricia" last="Ruiz">Patricia Ruiz</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre de Recherche du CHUL</s1><s3>FRA</s3><sZ>6 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>Centre de Recherche du CHUL</wicri:noRegion><wicri:noRegion>Centre de Recherche du CHUL</wicri:noRegion></affiliation></author><author><name sortKey="Wiles, Michael V" sort="Wiles, Michael V" uniqKey="Wiles M" first="Michael V." last="Wiles">Michael V. Wiles</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Max-Planck Institute of Molecular Genetics, Ihnestrasse</s1><s2>Berlin</s2><s3>DEU</s3><sZ>7 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Sousa Nunes, Rita" sort="Sousa Nunes, Rita" uniqKey="Sousa Nunes R" first="Rita" last="Sousa-Nunes">Rita Sousa-Nunes</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Laboratory of Mammalian Development, National Institute for Medical Research, The Ridgeway</s1><s2>Mill Hill, London</s2><s3>GBR</s3><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Kettleborough, Ross" sort="Kettleborough, Ross" uniqKey="Kettleborough R" first="Ross" last="Kettleborough">Ross Kettleborough</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Laboratory of Mammalian Development, National Institute for Medical Research, The Ridgeway</s1><s2>Mill Hill, London</s2><s3>GBR</s3><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Rana, Amer" sort="Rana, Amer" uniqKey="Rana A" first="Amer" last="Rana">Amer Rana</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Laboratory of Mammalian Development, National Institute for Medical Research, The Ridgeway</s1><s2>Mill Hill, London</s2><s3>GBR</s3><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Morissette, Jean" sort="Morissette, Jean" uniqKey="Morissette J" first="Jean" last="Morissette">Jean Morissette</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre de Recherche du CHUL</s1><s3>FRA</s3><sZ>6 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>Centre de Recherche du CHUL</wicri:noRegion><wicri:noRegion>Centre de Recherche du CHUL</wicri:noRegion></affiliation></author><author><name sortKey="Bentley, Liz" sort="Bentley, Liz" uniqKey="Bentley L" first="Liz" last="Bentley">Liz Bentley</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Goldsworthy, Michelle" sort="Goldsworthy, Michelle" uniqKey="Goldsworthy M" first="Michelle" last="Goldsworthy">Michelle Goldsworthy</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Haynes, Alison" sort="Haynes, Alison" uniqKey="Haynes A" first="Alison" last="Haynes">Alison Haynes</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Herbert, Eifion" sort="Herbert, Eifion" uniqKey="Herbert E" first="Eifion" last="Herbert">Eifion Herbert</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Southam, Lorraine" sort="Southam, Lorraine" uniqKey="Southam L" first="Lorraine" last="Southam">Lorraine Southam</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Lehrach, Hans" sort="Lehrach, Hans" uniqKey="Lehrach H" first="Hans" last="Lehrach">Hans Lehrach</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Max-Planck Institute of Molecular Genetics, Ihnestrasse</s1><s2>Berlin</s2><s3>DEU</s3><sZ>7 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Weissenbach, Jean" sort="Weissenbach, Jean" uniqKey="Weissenbach J" first="Jean" last="Weissenbach">Jean Weissenbach</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Genoscope, Centre National de Sequençage and CNRS UMR 8030, CP 5706</s1><s2>91057 Evry</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>91057 Evry</wicri:noRegion><wicri:noRegion>CP 5706</wicri:noRegion><wicri:noRegion>91057 Evry</wicri:noRegion></affiliation></author><author><name sortKey="Manenti, Giacomo" sort="Manenti, Giacomo" uniqKey="Manenti G" first="Giacomo" last="Manenti">Giacomo Manenti</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Instituto Nazionale Tumori, Division of Oncology</s1><s2>Milano</s2><s3>ITA</s3><sZ>19 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Rodriguez Tome, Patricia" sort="Rodriguez Tome, Patricia" uniqKey="Rodriguez Tome P" first="Patricia" last="Rodriguez-Tome">Patricia Rodriguez-Tome</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>The European Bioinformatics Institute, European Molecular Biology Laboratory Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus</s1><s2>Hinxton, Cambridge</s2><s3>GBR</s3><sZ>20 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Hinxton, Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Beddington, Rosa" sort="Beddington, Rosa" uniqKey="Beddington R" first="Rosa" last="Beddington">Rosa Beddington</name></author><author><name sortKey="Dunwoodie, Sally" sort="Dunwoodie, Sally" uniqKey="Dunwoodie S" first="Sally" last="Dunwoodie">Sally Dunwoodie</name><affiliation wicri:level="3"><inist:fA14 i1="09"><s1>The Victor Chang Cardiac Research Institute</s1><s2>Darlinghurst, Sydney</s2><s3>AUS</s3><sZ>22 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Cox, Roger D" sort="Cox, Roger D" uniqKey="Cox R" first="Roger D." last="Cox">Roger D. Cox</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">02-0311107</idno><date when="2001">2001</date><idno type="stanalyst">PASCAL 02-0311107 INIST</idno><idno type="RBID">Pascal:02-0311107</idno><idno type="wicri:Area/PascalFrancis/Corpus">005756</idno><idno type="wicri:Area/PascalFrancis/Curation">000983</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">005976</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">005976</idno><idno type="wicri:doubleKey">1061-4036:2001:Avner P:a:radiation:hybrid</idno><idno type="wicri:Area/Main/Merge">00CD21</idno><idno type="wicri:Area/Main/Curation">00BE12</idno><idno type="wicri:Area/Main/Exploration">00BE12</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">A radiation hybrid transcript map of the mouse genome</title><author><name sortKey="Avner, Philip" sort="Avner, Philip" uniqKey="Avner P" first="Philip" last="Avner">Philip Avner</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Genoscope, Centre National de Sequençage and CNRS UMR 8030, CP 5706</s1><s2>91057 Evry</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region" nuts="2">Île-de-France</region><settlement type="city">Evry</settlement></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Unité de Génétique Moléculaire Murine, Institut Pasteur</s1><s2>Paris</s2><s3>FRA</s3><sZ>1 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Bruls, Thomas" sort="Bruls, Thomas" uniqKey="Bruls T" first="Thomas" last="Bruls">Thomas Bruls</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Genoscope, Centre National de Sequençage and CNRS UMR 8030, CP 5706</s1><s2>91057 Evry</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>91057 Evry</wicri:noRegion><wicri:noRegion>CP 5706</wicri:noRegion><wicri:noRegion>91057 Evry</wicri:noRegion></affiliation></author><author><name sortKey="Poras, Isabelle" sort="Poras, Isabelle" uniqKey="Poras I" first="Isabelle" last="Poras">Isabelle Poras</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Genoscope, Centre National de Sequençage and CNRS UMR 8030, CP 5706</s1><s2>91057 Evry</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>91057 Evry</wicri:noRegion><wicri:noRegion>CP 5706</wicri:noRegion><wicri:noRegion>91057 Evry</wicri:noRegion></affiliation></author><author><name sortKey="Eley, Lorraine" sort="Eley, Lorraine" uniqKey="Eley L" first="Lorraine" last="Eley">Lorraine Eley</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Gas, Shahinaz" sort="Gas, Shahinaz" uniqKey="Gas S" first="Shahinaz" last="Gas">Shahinaz Gas</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Genoscope, Centre National de Sequençage and CNRS UMR 8030, CP 5706</s1><s2>91057 Evry</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>91057 Evry</wicri:noRegion><wicri:noRegion>CP 5706</wicri:noRegion><wicri:noRegion>91057 Evry</wicri:noRegion></affiliation></author><author><name sortKey="Ruiz, Patricia" sort="Ruiz, Patricia" uniqKey="Ruiz P" first="Patricia" last="Ruiz">Patricia Ruiz</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre de Recherche du CHUL</s1><s3>FRA</s3><sZ>6 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>Centre de Recherche du CHUL</wicri:noRegion><wicri:noRegion>Centre de Recherche du CHUL</wicri:noRegion></affiliation></author><author><name sortKey="Wiles, Michael V" sort="Wiles, Michael V" uniqKey="Wiles M" first="Michael V." last="Wiles">Michael V. Wiles</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Max-Planck Institute of Molecular Genetics, Ihnestrasse</s1><s2>Berlin</s2><s3>DEU</s3><sZ>7 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Sousa Nunes, Rita" sort="Sousa Nunes, Rita" uniqKey="Sousa Nunes R" first="Rita" last="Sousa-Nunes">Rita Sousa-Nunes</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Laboratory of Mammalian Development, National Institute for Medical Research, The Ridgeway</s1><s2>Mill Hill, London</s2><s3>GBR</s3><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Kettleborough, Ross" sort="Kettleborough, Ross" uniqKey="Kettleborough R" first="Ross" last="Kettleborough">Ross Kettleborough</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Laboratory of Mammalian Development, National Institute for Medical Research, The Ridgeway</s1><s2>Mill Hill, London</s2><s3>GBR</s3><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Rana, Amer" sort="Rana, Amer" uniqKey="Rana A" first="Amer" last="Rana">Amer Rana</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Laboratory of Mammalian Development, National Institute for Medical Research, The Ridgeway</s1><s2>Mill Hill, London</s2><s3>GBR</s3><sZ>8 aut.</sZ><sZ>9 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Royaume-Uni</country><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Morissette, Jean" sort="Morissette, Jean" uniqKey="Morissette J" first="Jean" last="Morissette">Jean Morissette</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Centre de Recherche du CHUL</s1><s3>FRA</s3><sZ>6 aut.</sZ><sZ>11 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>Centre de Recherche du CHUL</wicri:noRegion><wicri:noRegion>Centre de Recherche du CHUL</wicri:noRegion></affiliation></author><author><name sortKey="Bentley, Liz" sort="Bentley, Liz" uniqKey="Bentley L" first="Liz" last="Bentley">Liz Bentley</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Goldsworthy, Michelle" sort="Goldsworthy, Michelle" uniqKey="Goldsworthy M" first="Michelle" last="Goldsworthy">Michelle Goldsworthy</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Haynes, Alison" sort="Haynes, Alison" uniqKey="Haynes A" first="Alison" last="Haynes">Alison Haynes</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Herbert, Eifion" sort="Herbert, Eifion" uniqKey="Herbert E" first="Eifion" last="Herbert">Eifion Herbert</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Southam, Lorraine" sort="Southam, Lorraine" uniqKey="Southam L" first="Lorraine" last="Southam">Lorraine Southam</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author><author><name sortKey="Lehrach, Hans" sort="Lehrach, Hans" uniqKey="Lehrach H" first="Hans" last="Lehrach">Hans Lehrach</name><affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Max-Planck Institute of Molecular Genetics, Ihnestrasse</s1><s2>Berlin</s2><s3>DEU</s3><sZ>7 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="3">Berlin</region><settlement type="city">Berlin</settlement></placeName></affiliation></author><author><name sortKey="Weissenbach, Jean" sort="Weissenbach, Jean" uniqKey="Weissenbach J" first="Jean" last="Weissenbach">Jean Weissenbach</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Genoscope, Centre National de Sequençage and CNRS UMR 8030, CP 5706</s1><s2>91057 Evry</s2><s3>FRA</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>18 aut.</sZ></inist:fA14><country>France</country><wicri:noRegion>91057 Evry</wicri:noRegion><wicri:noRegion>CP 5706</wicri:noRegion><wicri:noRegion>91057 Evry</wicri:noRegion></affiliation></author><author><name sortKey="Manenti, Giacomo" sort="Manenti, Giacomo" uniqKey="Manenti G" first="Giacomo" last="Manenti">Giacomo Manenti</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Instituto Nazionale Tumori, Division of Oncology</s1><s2>Milano</s2><s3>ITA</s3><sZ>19 aut.</sZ></inist:fA14><country>Italie</country><wicri:noRegion>Milano</wicri:noRegion></affiliation></author><author><name sortKey="Rodriguez Tome, Patricia" sort="Rodriguez Tome, Patricia" uniqKey="Rodriguez Tome P" first="Patricia" last="Rodriguez-Tome">Patricia Rodriguez-Tome</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>The European Bioinformatics Institute, European Molecular Biology Laboratory Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus</s1><s2>Hinxton, Cambridge</s2><s3>GBR</s3><sZ>20 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Hinxton, Cambridge</wicri:noRegion></affiliation></author><author><name sortKey="Beddington, Rosa" sort="Beddington, Rosa" uniqKey="Beddington R" first="Rosa" last="Beddington">Rosa Beddington</name></author><author><name sortKey="Dunwoodie, Sally" sort="Dunwoodie, Sally" uniqKey="Dunwoodie S" first="Sally" last="Dunwoodie">Sally Dunwoodie</name><affiliation wicri:level="3"><inist:fA14 i1="09"><s1>The Victor Chang Cardiac Research Institute</s1><s2>Darlinghurst, Sydney</s2><s3>AUS</s3><sZ>22 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region></placeName></affiliation></author><author><name sortKey="Cox, Roger D" sort="Cox, Roger D" uniqKey="Cox R" first="Roger D." last="Cox">Roger D. Cox</name><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Mammalian Genetics Unit, Medical Research Council</s1><s2>Harwell</s2><s3>GBR</s3><sZ>4 aut.</sZ><sZ>12 aut.</sZ><sZ>13 aut.</sZ><sZ>14 aut.</sZ><sZ>15 aut.</sZ><sZ>16 aut.</sZ><sZ>23 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Harwell</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Nature genetics</title><title level="j" type="abbreviated">Nat. genet.</title><idno type="ISSN">1061-4036</idno><imprint><date when="2001">2001</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Nature genetics</title><title level="j" type="abbreviated">Nat. genet.</title><idno type="ISSN">1061-4036</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Genome</term><term>Hybrid</term><term>Mouse</term><term>Radiation</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Rayonnement</term><term>Hybride</term><term>Souris</term><term>Génome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Expressed-sequence tag (EST) maps are an adjunct to sequence-based analytical methods of gene detection and localization for those species for which such data are available, and provide anchors for high-density homology and orthology mapping in species for which large-scale sequencing has yet to be done<sup>1</sup>. Species for which radiation hybrid-based transcript maps have been established include human<sup>2</sup>, rat<sup>3-5</sup>, mouse<sup>6</sup>, dog<sup>7</sup>, cat<sup>8</sup> and zebrafish<sup>9,10</sup>. We have established a comprehensive first-generation-placement radiation hybrid map of the mouse consisting of 5,904 mapped markers (3,993 ESTs and 1,911 sequence-tagged sites (STSs)). The mapped ESTs, which often originate from small-EST clusters, are enriched for genes expressed during early mouse embryogenesis and are probably different from those localized in humans. We have confirmed by in situ hybridization that even singleton ESTs, which are usually not retained for mapping studies, may represent bona fide transcribed sequences. Our studies on mouse chromosomes 12 and 14 orthologous to human chromosome 14 show the power of our radiation hybrid map as a predictive tool for orthology mapping in humans.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>France</li><li>Italie</li><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Berlin</li><li>Grand Londres</li><li>Nouvelle-Galles du Sud</li><li>Île-de-France</li></region><settlement><li>Berlin</li><li>Evry</li><li>Londres</li><li>Paris</li><li>Sydney</li></settlement></list><tree><noCountry><name sortKey="Beddington, Rosa" sort="Beddington, Rosa" uniqKey="Beddington R" first="Rosa" last="Beddington">Rosa Beddington</name></noCountry><country name="France"><region name="Île-de-France"><name sortKey="Avner, Philip" sort="Avner, Philip" uniqKey="Avner P" first="Philip" last="Avner">Philip Avner</name></region><name sortKey="Avner, Philip" sort="Avner, Philip" uniqKey="Avner P" first="Philip" last="Avner">Philip Avner</name><name sortKey="Bruls, Thomas" sort="Bruls, Thomas" uniqKey="Bruls T" first="Thomas" last="Bruls">Thomas Bruls</name><name sortKey="Gas, Shahinaz" sort="Gas, Shahinaz" uniqKey="Gas S" first="Shahinaz" last="Gas">Shahinaz Gas</name><name sortKey="Morissette, Jean" sort="Morissette, Jean" uniqKey="Morissette J" first="Jean" last="Morissette">Jean Morissette</name><name sortKey="Poras, Isabelle" sort="Poras, Isabelle" uniqKey="Poras I" first="Isabelle" last="Poras">Isabelle Poras</name><name sortKey="Ruiz, Patricia" sort="Ruiz, Patricia" uniqKey="Ruiz P" first="Patricia" last="Ruiz">Patricia Ruiz</name><name sortKey="Weissenbach, Jean" sort="Weissenbach, Jean" uniqKey="Weissenbach J" first="Jean" last="Weissenbach">Jean Weissenbach</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Eley, Lorraine" sort="Eley, Lorraine" uniqKey="Eley L" first="Lorraine" last="Eley">Lorraine Eley</name></noRegion><name sortKey="Bentley, Liz" sort="Bentley, Liz" uniqKey="Bentley L" first="Liz" last="Bentley">Liz Bentley</name><name sortKey="Cox, Roger D" sort="Cox, Roger D" uniqKey="Cox R" first="Roger D." last="Cox">Roger D. Cox</name><name sortKey="Goldsworthy, Michelle" sort="Goldsworthy, Michelle" uniqKey="Goldsworthy M" first="Michelle" last="Goldsworthy">Michelle Goldsworthy</name><name sortKey="Haynes, Alison" sort="Haynes, Alison" uniqKey="Haynes A" first="Alison" last="Haynes">Alison Haynes</name><name sortKey="Herbert, Eifion" sort="Herbert, Eifion" uniqKey="Herbert E" first="Eifion" last="Herbert">Eifion Herbert</name><name sortKey="Kettleborough, Ross" sort="Kettleborough, Ross" uniqKey="Kettleborough R" first="Ross" last="Kettleborough">Ross Kettleborough</name><name sortKey="Rana, Amer" sort="Rana, Amer" uniqKey="Rana A" first="Amer" last="Rana">Amer Rana</name><name sortKey="Rodriguez Tome, Patricia" sort="Rodriguez Tome, Patricia" uniqKey="Rodriguez Tome P" first="Patricia" last="Rodriguez-Tome">Patricia Rodriguez-Tome</name><name sortKey="Sousa Nunes, Rita" sort="Sousa Nunes, Rita" uniqKey="Sousa Nunes R" first="Rita" last="Sousa-Nunes">Rita Sousa-Nunes</name><name sortKey="Southam, Lorraine" sort="Southam, Lorraine" uniqKey="Southam L" first="Lorraine" last="Southam">Lorraine Southam</name></country><country name="Allemagne"><region name="Berlin"><name sortKey="Wiles, Michael V" sort="Wiles, Michael V" uniqKey="Wiles M" first="Michael V." last="Wiles">Michael V. Wiles</name></region><name sortKey="Lehrach, Hans" sort="Lehrach, Hans" uniqKey="Lehrach H" first="Hans" last="Lehrach">Hans Lehrach</name></country><country name="Italie"><noRegion><name sortKey="Manenti, Giacomo" sort="Manenti, Giacomo" uniqKey="Manenti G" first="Giacomo" last="Manenti">Giacomo Manenti</name></noRegion></country><country name="Australie"><region name="Nouvelle-Galles du Sud"><name sortKey="Dunwoodie, Sally" sort="Dunwoodie, Sally" uniqKey="Dunwoodie S" first="Sally" last="Dunwoodie">Sally Dunwoodie</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 00BE12 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 00BE12 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= Pascal:02-0311107
|texte= A radiation hybrid transcript map of the mouse genome
}}
| This area was generated with Dilib version V0.6.33. |  |